Skip to main content
  • About ELGA
    • About ELGA
    • Ultrapure Water
    • Purification Technologies
    • Impurities In Water
    • Guides & White Papers
    • Approved Partners
    • ELGA's History
    • Sustainability
    • Careers
    • Events
  • Blog
    • Analytical Chemistry
    • Clinical & Pharma
    • Cool Science
    • Environment and sustainability
    • Life in the lab
    • Purelab product design
    • Science of the future
    • Water Purity
    • Water in the lab
  • Contact
  • Language
    • Deutsch
    • English
    • Español
    • Français
    • Italiano
    • Português
    • 日本語
    • 中文
  • Other Veolia Sites
    • Veolia
    • Veolia Fondation
    • Veolia Water Technologies
Home ELGA LabWater
  • Products
  • Applications
  • Case Studies
  • Support
  • Products
    • PURELAB
    • CENTRA
    • MEDICA
    • BIOPURE
    • ELGA Full Product Range
  • Applications
  • Case Studies
    • Unlocking the secrets of the Antarctic with the aid of ultrapure water
    • Abbott Diagnostics chooses ELGA MEDICA systems in South Asia
    • Ca’Foscari University- A New Method for Investigating Environmental Tracers in Ice
    • Ca’Foscari University- Investigating Contaminants in Antarctic Ice
    • DASA: The biggest medical diagnostics company in Brazil
    • ELGA helps immuneserology labs maximize uptime
    • Importance of ultrapure Type 1+ water for the development of generic medicines
    • MEDICA® Pro selected for Siemens ADVIA® analyzers at City General Hospital
    • Optimale Wasserqualität für mikrobiologische Forschung und Lehre
    • PURELAB® flex: an ideal training system for today's research method
    • Sichere Reinstwasserversorgung für präzise Produkttests
    • Zentrale Reinstwasser-Aufbereitung für Analyser
  • Support
    • Support & Services
    • Laboratory Planning
    • Register a Product
    • Register Your Product (USA & Canada Only)
  • Products
    • PURELAB
      • PURELAB Chorus 1 Complete
      • PURELAB® Chorus 1
      • PURELAB Chorus 2+
      • PURELAB® Chorus 2
      • PURELAB® Chorus 3
      • PURELAB® flex 1 & 2
      • PURELAB® flex 3 & 4
    • CENTRA
      • CENTRA® 60/120
      • CENTRA® RDS
      • CENTRA® R200
    • MEDICA
      • MEDICA® 7/15
      • MEDICA® EDI 15/30
      • MEDICA® Pro EDI 60/120
      • MEDICA® Pro-LPS
      • MEDICA® Pro-R and Pro-RE
      • MEDICA® R200
    • BIOPURE
      • BIOPURE 7/15
      • BIOPURE 60/120
      • BIOPURE 200/300/600
    • ELGA Full Product Range
      • PURELAB® Classic
  • Applications
  • Case Studies
    • Unlocking the secrets of the Antarctic with the aid of ultrapure water
    • Abbott Diagnostics chooses ELGA MEDICA systems in South Asia
    • Ca’Foscari University- A New Method for Investigating Environmental Tracers in Ice
    • Ca’Foscari University- Investigating Contaminants in Antarctic Ice
    • DASA: The biggest medical diagnostics company in Brazil
    • ELGA helps immuneserology labs maximize uptime
    • Importance of ultrapure Type 1+ water for the development of generic medicines
    • MEDICA® Pro selected for Siemens ADVIA® analyzers at City General Hospital
    • Optimale Wasserqualität für mikrobiologische Forschung und Lehre
    • PURELAB® flex: an ideal training system for today's research method
    • Sichere Reinstwasserversorgung für präzise Produkttests
    • Zentrale Reinstwasser-Aufbereitung für Analyser
  • Support
    • Support & Services
    • Laboratory Planning
    • Register a Product
    • Register Your Product (USA & Canada Only)
  • Language
    • Deutsch
    • English
    • Español
    • Français
    • Italiano
    • Português
    • 日本語
    • 中文
  • Other Veolia Sites
    • Veolia
    • Veolia Fondation
    • Veolia Water Technologies
  • Privacy policy
  • Terms & Conditions
  • Global Legal Compliance
  • Patents
  • Sitemap
  • Impressum

Let's talk about lab water

  • Categories
    • Analytical Chemistry
    • Clinical & Pharma
    • Cool Science
    • Environment & Sustainability
    • Future Science
    • Life in The Lab
    • PURELAB Product Design
    • Science of the Future
    • Water In The Lab
    • Water Purity
  • Authors
    • ELGA Editorial Team
    • Natasha Zarach
    • Dr Paul Whitehead
    • Dr Alison Halliday
    • John Walker
Future Science
Analytical Chemistry

Screening Formulations for New 3D Printed Wound Healing Materials

1 Dec 2019
- by Dr Alison Halliday

3D Skin CellA new study investigates a fast, simple and cost-effective new platform for evaluating the impact of adding growth factors to formulations intended for innovative 3D-printed wound healing materials.

Researchers working in the field of regenerative medicine are applying our ever-increasing knowledge of the biological processes involved in tissue repair to develop new and improved wound healing solutions. Many are currently focused on 3D printing and bio-printing technologies, which work by patterning biomaterials, biomolecules and/or cells to create materials that mimic the complexity of skin tissues and help promote the body’s natural wound healing processes.

Growth factors – including epidermal growth factor (EGF), fibroblast growth factor (FGF) and platelet-derived growth factor (PDGF) – are intrinsically involved in orchestrating several aspects of these processes. So incorporating these molecules into new wound dressings is a logical step to improve their healing potential. But as these are expensive ingredients, strong evidence is needed to prove that the benefits outweigh the costs.

A New Film-Based Testing Platform

In a new study, published in Applied Surface Science, a team of scientists explore the use of thin polysaccharide blend thin films to test the impact of including growth factors into formulations intended for 3D bio-printed wound healing materials.1 The researchers created blended alginate/carboxymethyl cellulose-based thin films loaded with and without growth factors and evaluated several of their properties at a nano-level.They analysed film formation using ATR-IR spectroscopy, evaluated their surface morphology and topography by atomic force and scanning electron microscopies. They determined their hydrophilicity using the water contact angle measurement method. Their results showed that adding growth factors into the blend films did not affect their formation or morphology, while their hydrophilicity was even slightly enhanced.

The team next set out to evaluate the function and influence of the blend films on potential wound care applications in cultured human skin cell experiments. They found that the growth factors boosted cell viability. This is promising for both their own potential for use in wound healing as well as their application as testing platforms to find suitable materials for other types of wound-care products, such as 3D bio-printed materials.They used ultrapure water prepared from an ELGA PURELAB® laboratory water purification system for the preparation of all their solutions, minimising the risk of introducing contaminants that could affect the results of their experiments.

Cost-Effective, Simple and Quick

These encouraging results suggest that these blended thin films may represent a simple, yet systematic and representative platform that can reduce costs and speed up the development of novel growth factor-loaded formulations for 3D bio-printing or other wound care solutions. Although further studies will be necessary to project the performance determined using the thin films to 3D-printed growth factor-loaded wound dressings, this approach shows great promise for a robust way to evaluate and refine new formulations for use in wound healing.

Why choose ELGA LabWater?

ELGA are the LabWater Specialists, for over 80 years we have been working with scientists to guarantee pure and ultrapure water for their experiments and lab work. Laboratories around the world trust our water purification systems to help their researchers to achieve accurate, reliable, quality results.

 

Reference:
1. Maver, U. et. al. Impact of growth factors on wound healing in polysaccharide blend thin films. Applied Surface Science; 2019: 485-49.

 

Dr Alison Halliday
After completing an undergraduate degree in Biochemistry & Genetics at Sheffield University, Alison was awarded a PhD in Human Molecular Genetics at the University of Newcastle. She carried out five years as a Senior Postdoctoral Research Fellow at UCL, investigating the genes involved in childhood obesity syndrome. Moving into science communications, she spent ten years at Cancer Research UK engaging the public about the charity’s work. She now specialises in writing about research across the life sciences, medicine and health.

You may also be interested in...

Highlights

8 Dec 2019
Research into Silver Nanoparticles
1 Dec 2019
Screening Formulations for New 3D Printed Wound Healing Materials
24 Nov 2019
Using ‘Molecular Bar Codes’ To Tackle The Problem Of Counterfeit Drugs
18 Nov 2019
Extracting Bioactive Compounds from Pomegranate Peel
30 Apr 2019
An Ultra-Sensitive New DNA Sensor for Detecting and Diagnosing Genetic Diseases
30 Apr 2019
Developing a New Diagnostic Test for an Aggressive Childhood Cancer
30 Apr 2019
New Synthetic Cannabinoid Discovered in ‘e-liquids’ for Clectronic Cigarettes
30 Apr 2019
Using hair samples to monitor exposure to alternative plasticisers

Categories

  • Analytical Chemistry
  • Clinical & Pharma
  • Cool Science
  • Environment & Sustainability
  • Future Science
  • Life in The Lab
  • PURELAB Product Design
  • Science of the Future
  • Water In The Lab
  • Water Purity

Video

  • Contact Us
  • Get a Quote
  • Book a Demo
  • Find an Approved Partner

Contact Us

At ELGA LabWater, we have exciting offers and news about our lab water purification products that we hope you’d like to hear about. We will use your information to predict what you might be interested in. We will treat your data with respect and you can find the details in our Privacy Policy here.

ELGA Labwater works with a network of Approved Partners. In order to answer your questions or inquiries, we may pass your contact details to an Approved Partner, who may contact you directly. You can find a list of our Approved Business Partners here.

If you would like to receive updates from ELGA and our Approved partners please tick the box below:

YES I'd like to receive updates from ELGA LabWater & Approved Partners based on my details

Get a Quote

At ELGA LabWater, we have exciting offers and news about our lab water purification products that we hope you’d like to hear about. We will use your information to predict what you might be interested in. We will treat your data with respect and you can find the details in our Privacy Policy here.

ELGA Labwater works with a network of Approved Partners. In order to answer your questions or inquiries, we may pass your contact details to an Approved Partner, who may contact you directly. You can find a list of our Approved Business Partners here.

If you would like to receive updates from ELGA and our Approved partners please tick the box below:

YES I'd like to receive updates from ELGA LabWater & Approved Partners based on my details

Book a Demo

At ELGA LabWater, we have exciting offers and news about our lab water purification products that we hope you’d like to hear about. We will use your information to predict what you might be interested in. We will treat your data with respect and you can find the details in our Privacy Policy here.

ELGA Labwater works with a network of Approved Partners. In order to answer your questions or inquiries, we may pass your contact details to an Approved Partner, who may contact you directly. You can find a list of our Approved Business Partners here.

If you would like to receive updates from ELGA and our Approved partners please tick the box below:

YES I'd like to receive updates from ELGA LabWater & Approved Partners based on my details

ELGA LabWater Head Quarters

Lane End Business Park
Lane End, High Wycombe
HP14 3BY
United Kingdom
T: +44 (0) 203 567 7300
F: +44 (0) 203 567 7205

The Ultrapure Water Specialists

  • Company History
  • Support & Services
  • Events

Case Studies

  • Abbott Diagnostics
  • DASA Medical Diagnostics
  • NeoDIN Medical Institute
  • North Staffordshire NHS Trust
  • Olsberg Vocational College

Resources

  • Learn About Ultrapure Water
  • Guides and White Papers
  • Purification Technologies
  • Applications
  • Impurities In Water

Blogs

  • Latest Blog
  • Water Purity - Different Types of Pure Water
  • What is Clinical Laboratory Reagent Water (CLSI)?
  • What is Total Organic Carbon (TOC)?
  • Language
    • Deutsch
    • English
    • Español
    • Français
    • Italiano
    • Português
    • 日本語
    • 中文
  • Other Veolia Sites
    • Veolia
    • Veolia Fondation
    • Veolia Water Technologies

© VWS (UK) Ltd. trading as ELGA LabWater. 2019 - All rights reserved.
ELGA is the global laboratory water brand name of Veolia.

  • Privacy policy
  • Terms & Conditions
  • Global Legal Compliance
  • Patents
  • Sitemap
  • Impressum
Elga Veolia
TOP

© 2017 ELGA Veolia